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For instance, an IgG-Fc conjugated ancestral Wuhan-Hu-1 RBD sequence adjuvanted with a novel STING agonist CF501 induced potent nAb activity against SARS-CoV-2 Omicron and XBB variants in macaques, mice, and rabbits [159, 160] (Table 2)

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While traditionally considered as cytosolic enzymes, work in Arabidopsis has revealed that several isoforms may localize at least partly to other compartments, including the chloroplast, peroxisome, and nucleus (Thatcher et al., 2007